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Fasciculation anxiety syndrome in clinicians.

PostPosted: August 31st, 2014, 1:24 pm
by misterjuanperalta

The goal of this study is to define the clinical features, pathogenesis and key investigation findings of fasciculation anxiety syndrome in clinicians (FASICS). Twenty consecutive clinicians presenting with fasciculations were prospectively assessed with serial clinical and neurophysiological evaluations. Clinicians with fasciculations formed three groups: 70 % of clinicians experienced symptomatic fasciculations and anxiety about the possibility of amyotrophic lateral sclerosis (ALS), termed FASICS; a further 15 % of clinicians experienced fasciculations associated with cramps and consistent with cramp-fasciculation syndrome (CFS). The final 15 % of clinicians presented with fasciculations associated with sensory symptoms or muscle weakness and were diagnosed with neuropathy (10 %) and ALS (5 %). In FASICS, fasciculations most often involved the lower limbs, without evidence of muscle weakness on clinical examination. Exercise, stress, fatigue and caffeine consumption were identified as common exacerbating factors. Neurophysiological studies confirmed normal nerve conduction studies and the presence of simple fasciculations, without acute denervation or neurogenic motor unit changes. Antibodies to voltage-gated potassium channels were assayed in each clinician and were not detected, and systemic autoantibodies were detected only in clinicians with features of CFS. FASICS is a disorder common among physicians presenting for evaluation of fasciculations. The present study delineates the diagnostic features of FASICS and contrasts the clinical presentation with other causes of fasciculations in clinicians. (J Neurol. 2013 Jul;260(7):1743-7. doi: 10.1007/s00415-013-6856-8. Epub 2013 Feb 12.)


Re: Fasciculation anxiety syndrome in clinicians.

PostPosted: August 31st, 2014, 4:55 pm
by J4son
That study has already been mentioned several times on this forum (Check the archives) and It shows 2 things:

1) That clinicians are prone to developing anxiety over twitching because they are aware of the link between ALS and twitching while normal people are not. since the start of the internet era most people have access to medical literature on the web and so are acting like those clinicians.

2) This study confirms what we already know about twitching and ALS since among the 20 clinicians involved in the study:

- 14 of them (70%) had twitching and anxiety alone and were diagnosed with fasciculations anxiety syndrome in clinicians (FASICS).
- 3 of them (15%) had fasciculations and cramps and were diagnosed with cramp-fasciculation syndrome (CFS)
- 2 of them (10%) had fasciculations and sensory issues and were diagnosed with neuropathy.
- 1 of them (5%) had fasciculations and weakness and was diagnosed with ALS.

Conclusion: Twitching without clinical weakness is benign.

Re: Fasciculation anxiety syndrome in clinicians.

PostPosted: September 1st, 2014, 8:44 am
by Little Lost
Hi Mr j..

Previous discussion about paper if you are interested. I particularly like Mario M last post about the true meaning of BFS.....I.e.*beep*.


Re: Fasciculation anxiety syndrome in clinicians.

PostPosted: September 1st, 2014, 9:39 am
by misterjuanperalta