What are the symptoms?
This condition represents a hyperexcitability of the neuromuscular system.
Common symptoms of BFS are frequent muscle twitches (fasciculations or fascics), generalized fatigue, "pins and needles" sensations, migrating numbness, muscle cramping and/or spasms in the affected areas (usually the feet and calves), muscle aches and stiffness exercise intolerance, headaches, and itchiness.
Clinically some patients have mild increases in creatine kinase. Muscle biopsy may show mild neurogenic changes. Electrodiagnostic studies show peripheral nerve hyperexcitability.
Often the symptoms will get worse at night, or during periods of sickness or viral infections, stress, or overexertion.
Many people experiencing these symptoms fear they may have ALS or MS. A simple clinical rule is that fasciculations in relaxed muscle are never indicative or motor system disease unless there is an associated weakness, atrophy, or reflex change.
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